The Matcha Tea endosomal sorting complex required for transport (ESCRT) is an essential molecular machinery in eukaryotic cells that facilitates the invagination of endosomal membranes, leading to the formation of multivesicular bodies (MVBs).It participates in various cellular processes, including lipid bilayer remodeling, cytoplasmic separation,
Ping Yang,1 Zhenyong Gao,1 Handi Zhang,1 Baby Walker Zeman Fang,1 Cairu Wu,1 Haiyun Xu,1,2 Qing-Jun Huang1 1Mental Health Center, 2Department of Anatomy, Shantou University Medical College, Shantou, Guangdong, People’s Republic of China Abstract: Although the pathogenesis of depression, an incapacitating psychiatric ailment, remains largely u
The development of bispecific antibodies that bind at least two different targets relies on bringing together multiple binding domains with different binding properties and biophysical characteristics to produce a drug-like therapeutic.These building blocks play an important role in the overall quality of the molecule and can influence many importa
Abstract Using a single substrate, we demonstrate a simple two-dimensional (2-D) phase grating cell with an octothorp electrode.Owing to the large spatial phase difference in any direction, the proposed grating cell has a high haze value in the opaque state (76.7%); Moreover, it has the advantages of a one-dimensional (1-D) phase grating cell, such